In my PhD in the James lab, my supervisors are David James and Benjamin Parker and I am interested in how muscle responds to exercise to cause beneficial effects. Exercise is one of the best prevention strategies for diseases such as obesity-related metabolic disease, cardiovascular disease and type-II diabetes. The health benefits of exercise are well established, however, our understanding of the molecular signalling events which regulate these benefits are poorly understood. I am interested in the underlying mechanisms of how kinases and signal transduction networks in skeletal muscle regulate metabolic pathways. To answer these questions, we perform mass spectrometry-based proteomic analysis of skeletal muscle and define kinase-substrate relationships with biochemical and bioinformatics approaches. Unveiling these mechanisms will uncover new therapeutic targets to modulate metabolism, which will improve treatment strategies for a range of diseases. Previously, in 2016, I graduated from BSc(Biochemisty)(Adv)(Hons I, Medal) from the University of Sydney and the James lab.