Hani Jieun Kim
Cells respond to diverse environmental cues via a multitude of signalling pathways. These signalling events underscore all cellular processes underlying human development and disease. I am interested in integrating omics data to understand how these regulatory and signalling networks function to establish identities of cells and make cell-fate decisions in early development. Currently, I am investigating novel roles for the core pluripotency network in mouse embryonic stem cells with collaborators at Children’s Medical Research Institute. Our trans-omic analyses have uncovered a more nuanced transcriptional network regulating the transition between pluripotent and primed states in stem cells. During my PhD studies, I aim to use my computational and biochemical skills to better understand trans-omic networks and their phenotypic consequences in various cell systems.
Previously, I graduated from Imperial College London (BSc in Biomedical Sciences) and, in 2014, from Seoul National University (MSc in Biological Sciences), where I was involved in investigating protein trafficking across the yeast secretory pathway and membrane protein biogenesis. Before joining the James Lab in 2018, I also worked as a professional medical writer (MWCTM) and editor (Editor in the Life Sciences).