Sean Humphrey, PhD
I completed undergraduate training as a pharmacologist at the University of New South Wales, and received a PhD in Cell Biology from David James’ laboratory at the Garvan Institute in 2013. After post-doctoral training at the Max Planck Institute for Biochemistry in Munich (Germany) in the Group of Matthias Mann, I joined the newly established Charles Perkins Centre at the University of Sydney where I am now a senior post-doctoral fellow in the group of David James. I have developed technologies for the detection of protein post-translational modifications (PTMs) with unprecedented throughput, and am applying these to address various unsolved questions in cell biology. My research interests are in mass spectrometry-based proteomics. My current work focuses on the development of quantitative mass spectrometric tools and technologies for systems-wide analysis of proteins and their modifications, and applying these methods to study disease-perturbed signalling networks.